van de Sandt CE, Dou Y, Vogelzang-van Trierum SE, Westgeest KB, Pronk MR, Osterhaus AD, Fouchier RA, Rimmelzwaan GF, Hillaire ML. (2015). Influenza B virus-specific CD8+ T lymphocytes strongly cross-react with viruses of the opposing influenza B lineage. The Journal of General Virology 96: 2061-2073
Category Archives: News
Universal Influenza Vaccines
Lidewij C. M. Wiersma , Guus F. Rimmelzwaan and Rory D. de Vries. (2015) Developing Universal Influenza Vaccines: Hitting the Nail, Not Just on the Head. Vaccine 2015, 3(2), 239-262.
GFP expressing influenza A virus
Sarah De Baets, Judith Verhelst, Silvie Van den Hoecke, Anouk Smet, Michael Schotsaert, Emma R. Job, Kenny Roose, Bert Schepens, Walter Fiers, and Xavier Saelens. (2015) A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody. PLoS One. 2015; 10(3): e0121491.
FLUNIVAC’s first newsletter is out!
T-cell responses are correlates of protection against influenza
Altenburg AF, Rimmelzwaan GF, de Vries RD. (2015) Virus-specific T cells as correlate of (cross-)protective immunity against influenza. Vaccine 33(4):500-506
Long-lived CD8 T-cell response against influenza
van de Sandt CE, Hillaire ML, Geelhoed-Mieras MM, Osterhaus AD, Fouchier RA, Rimmelzwaan GF. (2015) Human Influenza A Virus-Specific CD8+ T-Cell Response Is Long-lived. J Infect Dis. 2015 Jan 12. pii: jiv018. [Epub ahead of print]
Broad bispecific antibody against influenza virus
Wagner K, Kwakkenbos MJ, Claassen YB, Maijoor K, Böhne M, van der Sluijs KF, Witte MD, van Zoelen DJ, Cornelissen LA, Beaumont T, Bakker AQ, Ploegh HL, Spits H. (2014) Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity. Proc Natl Acad Sci U S A. 111(47):16820-5
Phase 1/2a clinical trials of MVA-based H5N1 vaccine
Joost H C M Kreijtz, Marco Goeijenbier, Fleur M Moesker, Lennert van den Dries, Simone Goeijenbier, Heidi L M De Gruyter, Michael H Lehmann, Gerrie de Mutsert, David A M C van de Vijver, Asisa Volz, Ron A M Fouchier, Eric C M van Gorp, Guus F Rimmelzwaan, Gerd Sutter, Albert D M E Osterhaus (2014) Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: a randomised, double-blind […]
Influenza vaccines against influenza-associated bacterial infection?
Ioanna Christopoulou, Kenny Roose, Lorena Itatí Ibañez, and Xavier Saelens (2014) Influenza vaccines to control influenza-associated bacterial infection: where do we stand? Expert Review of Vaccine doi:10.1586/14760584.2015.957191
Promising results in the Journal of Infectious Diseases!
J.H.C.M. Kreijtz, L.C.M. Wiersma, H.L.M. Gruyter De, S.E. Vogelzang-van Trierum, G. van Amerongen, K.J. Stittelaar, R.A.M. Fouchier, A.D.M.E. Osterhaus, G. Sutter and G.F. Rimmelzwaan (2014) A single immunization with a modified Vaccinia Virus Ankara-based influenza virus H7 vaccine affords protection in the influenza A(H7N9) pneumonia ferret model. The Journal of Infectious Diseases 10.1093/infdis/jiu528